Infertile women with fibroids have reduced fertility outcomes and benefit from fibroid removal, but the degree of impact depends on the type of fibroid, say US scientists.
David Olive, from the Wisconsin Fertility Institute in Middleton, and colleagues conducted a systematic literature review, analyzing data from 23 studies on the effects of fibroids on fertility and of myomectomy in improving outcomes.
Overall, fibroids significantly reduced the likelihood of clinical pregnancy, implantation, and ongoing pregnancy/live birth, at relative risks of 0.849, 0.821, and 0.697, respectively. They also increased the risk for spontaneous abortion, at a relative risk of 1.678. There was no significant impact on the preterm delivery rate.
Further analysis showed that women with subserosal fibroids had no differences in their fertility outcomes in comparison with infertile controls with no myomas, and myomectomy did not alter outcomes. In contrast, submucosal fibroids decreased clinical pregnancy and implantation rates and removal appeared to improve fertility.
With intramural fibroids, fertility was decreased and pregnancy loss was increased, but myomectomy did not significantly improve outcomes. However, data for intramural fibroids were scare and of poor quality.
"In summary, infertility patients with fibroids that impinge upon the endometrial cavity have poorer reproductive outcomes than those infertile patients without fibroids," the team concludes.

relating to TCM and Fibroids
great post Ray !
I know Bob Flaws would say that we can't use any western disease as a "pattern" in TCM diagnosis, although .... because they are finding that different fibroids are having different impacts on fertility maybe as the diagnosis gets more specific we could begin to make the cross over and say This type of fibroid relates to Blood Stasis, This type of Fibroid related to Phlegm Stagnation, This type of Fibroid is more commonly due to Qi stagnation, ...
Any thoughts?